Anti-IgM (mu) (wine), Fluorescein Conjugated

This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-fluorescein, anti-Rabbit Serum, Swine IgM and Swine Serum.  No reaction was observed against Swine IgG. Anti-Swine IgM antibody fluorescein conjugated generated in rabbit specifically detects swine IgM. Immunoglobulin M is the largest antibody isotype and the first to be secreted against an initial exposure to antigen. IgM is predominantly produced in the spleen. Formed from covalently linking 5 immunoglobulins together, the approximate molecular weight of IgM is 900kDa and possesses 10 binding sites (though due to the size of most antigens, not all sites are capable of binding at once). Due to this large size, IgM is typically isolated to the serum. Anti-swine IgM antibody is ideal for investigators in Immunology, Microbiology, and Cell Biology.