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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
REV-31-1026-00-C100 | 100 µg | - | - |
3 - 9 business days* |
483.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Recombinant Antibody. This antibody reacts to human IgA1, and very slightly cross reacts with... more
Product information "Anti-IgA1 (human), Rabbit Monoclonal (RM124)"
Recombinant Antibody. This antibody reacts to human IgA1, and very slightly cross reacts with IgA2. No cross reactivity with human IgG, IgM, IgD, or IgE. Applications: ICC, IHC, FACS, ELISA. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Immunoglobulin A (IgA) is an antibody isotype that plays a crucial role in the immune function of mucous membranes. IgA has two subclasses (IgA1 and IgA2) and can be produced as a monomeric as well as a dimeric form. The IgA dimeric form is the most prevalent and is also called secretory IgA (sIgA). sIgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes, thus, sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. In the blood, IgA interacts with the Fc receptor called FcalphaRI (or CD89), which is expressed on immune effector cells, to initiate inflammatory reactions. This anti-human secondary antibody has well-characterized specificity for human IgA1 immunoglobulins and is useful in the detection, sorting or purification of its specified target. In general, secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody.
Keywords: | Immunoglobulin A1 |
Supplier: | RevMAb Biosciences |
Supplier-Nr: | 31-1026-00 |
Properties
Application: | ICC, IHC, FC, ELISA |
Antibody Type: | Monoclonal |
Clone: | RM124 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Format: | Purified |
Database Information
UniProt ID : | P01876 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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