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![Anti-phospho-RPA2, (T21) (Replication Protein A2)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
R3402-05C.100 | 100 µg | - | - |
3 - 19 business days* |
871.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
RPA2 is a 32kD DNA-binding protein that constitutess one of three subunits comprising the PRA... more
Product information "Anti-phospho-RPA2, (T21) (Replication Protein A2)"
RPA2 is a 32kD DNA-binding protein that constitutess one of three subunits comprising the PRA heterotrimer complex. In conjunction with 70kD RPA1 and 14kD RPA3, RPA2 participates in DNA replication, recombination and repair. Human RPA2 is 270aa in length. It contains a Gly/Ser-rich N-terminus (aa1-33), a DNA-binding domain (aa43-171) and a protein-interaction C-terminus (aa187-270). Phosphorylation of the N-terminus on Ser4/8/23/29/33, plus Thr21, regulates RPA complex interactions with DNA repair and replication complexes. There are multiple splice variants. Three contain N-terminal extensions: one shows an 88aa insertion after Ser4, another shows a 12aa substitution for aa1-4, and a third shows a four aa insertion after Ser4. There is also a deletion of aa93-98, and a potential truncation after Gln175. Over aa141-270, human RPA2 shares 83% aa identity with mouse RPA2. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2, Anti-phospho-Replication factor A protein 2, Anti-phospho-Replication protein A 32 kDa subunit, Anti-phospho-Replication protein A 34 kDa subunit |
Supplier: | United States Biological |
Supplier-Nr: | R3402-05C |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic phosphopeptide corresponding to human RPA2 T21 (P15927). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10739 | Matching products |
UniProt ID : | P15927 | Matching products |
Gene ID | GeneID 6118 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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