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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P3123-03.100 | 100 µl | - | - |
3 - 19 business days* |
750.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal... more
Product information "Anti-phospho-PDK1 (Ser241) (Phosphoinositide-Dependent Protein Kinase-1)"
Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways, activating Akt, PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis. Several serine sites (Ser25, Ser241, Ser393/396 and Ser410) are phosphorylated on PDK1 in unstimulated human embryo kidney 293 cells, as well as IGF-1 stimulated cells (4). Phosphorylation on the activation loop Ser241 by autophosphorylation is necessary for PDK1 activity. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000. Incubate membrane with diluted antibody in TBS, 5% BSA, 0.1% Tween-20 at 4°C with gentle shaking, overnight., Immunoprecipitation: 1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | P3123-03 |
Properties
Application: | ELISA, IP, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
MW: | 63.00 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06276 | Matching products |
UniProt ID : | O15530 | Matching products |
Gene ID | GeneID 5170 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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