Anti-phospho-p62 (Ser207)

Anti-phospho-p62 (Ser207)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-F48756-0.08ML 80 µl - -

3 - 10 business days*

326.00€
NSJ-F48756-0.4ML 400 µl - -

3 - 10 business days*

702.00€
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a multifunctional protein that... more
Product information "Anti-phospho-p62 (Ser207)"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin- 1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. [The UniProt Consortium]
Keywords: Anti-phospho-p60, Anti-phospho-ORCA, Anti-phospho-EBIAP, Anti-phospho-SQSTM1, Anti-phospho-Sequestosome-1, Anti-phospho-Ubiquitin-binding protein p62, Anti-phospho-EBI3-associated protein of 60 kDa, Phospho-p62 Antibody (pS207)
Supplier: NSJ Bioreagents
Supplier-Nr: F48756

Properties

Application: Dot Blot, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: This phospho-p62 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS207 of human p62/SQSTM1.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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