Anti-phospho-Oct4 (Ser236)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F48631-0.08ML	80 µl		-	-	3 - 10 business days*		350.00€
NSJ-F48631-0.4ML	400 µl		-	-	3 - 10 business days*		755.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. OCT4 encodes a transcription factor containing a POU... more

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Product information "Anti-phospho-Oct4 (Ser236)"

In 1X PBS, pH 7.4, with 0.09% sodium azide. OCT4 encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. Protein function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. [The UniProt Consortium]

Keywords:	Anti-phospho-OCT3, Anti-phospho-Oct-4, Anti-phospho-Oct-3, Anti-phospho-OTF-3, Anti-phospho-POU5F1, Anti-phospho-Octamer-binding protein 3, Anti-phospho-Octamer-binding protein 4, Anti-phospho-Octamer-binding transcription factor 3, Phospho-Oct4 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	F48631

Properties

Application:	Dot Blot, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	This phospho-Oct4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS236 of human OCT4.
Format:	Purified