Anti-phospho-NMDAR2B (Tyr1474)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG51666.50	50 µl		-	-	6 - 14 business days*		460.00€
ARG51666.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium... more

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Product information "Anti-phospho-NMDAR2B (Tyr1474)"

Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]

Keywords:	Anti-phospho-NR3, Anti-phospho-hNR3, Anti-phospho-NR2B, Anti-phospho-GRIN2B, Anti-phospho-GluN2B, Anti-phospho-NMDAR2B, Anti-phospho-Glutamate receptor ionotropic, NMDA 2B, Anti-phospho-N-methyl-D-aspartate receptor subunit 3
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG51666

Properties

Application:	WB, ICC, IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around phosphorylation site of Tyr1474 (H-V-Y(p)-E-K) derived from Human NMDAR2B
Format:	Affinity Purified