Anti-phospho-MEK-2 (Thr394)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1007-50	50 µl		-		3 - 11 business days*		574.00€

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Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr... more

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Product information "Anti-phospho-MEK-2 (Thr394)"

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases. Protein function: Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases. Activates BRAF in a KSR1 or KSR2-dependent manner, by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (PubMed:29433126). [The UniProt Consortium]

Keywords:	Anti-phospho-MEK2, Anti-phospho-MEK 2, Anti-phospho-MAP2K2, Anti-phospho-MAPKK 2, Anti-phospho-MAPK/ERK kinase 2, Anti-phospho-MAP kinase kinase 2, Anti-phospho-ERK activator kinase 2, Polyclonal Antibody to MEK-2 (Phospho-Thr394)
Supplier:	Abeomics
Supplier-Nr:	35-1007-50

Properties

Application:	WB, IHC, IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Peptide sequence around phosphorylation site of threonine 394 (P-G-T(p)-P-T) derived from Human MEK-2.
Format:	Purified