Anti-phospho-Histone H2A.X (Ser139)

Promotion:

Save 30% on all primary antibodies by Arigo Biolaboratories!

^*1

^*1 Offer expires 16/12/2024

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG55251.100	100 µl		-	-	6 - 14 business days*		30 %	624.00€ 436.80€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.... more

Close menu

Product information "Anti-phospho-Histone H2A.X (Ser139)"

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation. [The UniProt Consortium]

Keywords:	Anti-phospho-H2AX, Anti-phospho-H2AFX, Anti-phospho-H2a/x, Anti-phospho-Histone H2AX, Anti-phospho-Histone H2A.X
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55251

Properties

Application:	WB, ICC, IF
Antibody Type:	Monoclonal
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse
Immunogen:	Synthetic phosphospecific peptide around Ser139 of Human H2A.X
MW:	15 kD
Format:	Antigen Affinity Purified