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![Anti-phospho-c-Abl (Tyr134) (ABL, Tyrosine-protein Kinase ABL1, Abelson Murine Leukemia Viral Oncoge](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C0013-04D-PE.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes... more
Product information "Anti-phospho-c-Abl (Tyr134) (ABL, Tyrosine-protein Kinase ABL1, Abelson Murine Leukemia Viral Oncoge"
ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. Applications: Suitable for use in FLISA, Western Blot, Dot Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Immunohistochemistry: 1:50-1:100, Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-phospho-ABL, Anti-phospho-ABL1, Anti-phospho-p150, EC=2.7.10.2, Anti-phospho-Proto-oncogene c-Abl, Anti-phospho-Tyrosine-protein kinase ABL1, Anti-phospho-Abelson tyrosine-protein kinase 1 |
Supplier: | United States Biological |
Supplier-Nr: | C0013-04D-PE |
Properties
Application: | FLISA, Dot Blot, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | Phycoerythrin |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr134 of human ABL1 (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06619 | Matching products |
UniProt ID : | P00519 | Matching products |
Gene ID | GeneID 25 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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