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![Anti-phospho-AKT1 (Ser129) (RAC-alpha Serine/Threonine-protein Kinase, RAC-PK-alpha, Protein Kinase](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A1125-11B-PE.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in... more
Product information "Anti-phospho-AKT1 (Ser129) (RAC-alpha Serine/Threonine-protein Kinase, RAC-PK-alpha, Protein Kinase"
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Applications: Suitable for use in FLISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Immunohistochemistry: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-phospho-PKB, Anti-phospho-AKT1, Anti-phospho-PKB alpha, EC=2.7.11.1, Anti-phospho-RAC-PK-alpha, Anti-phospho-Protein kinase B, Anti-phospho-Proto-oncogene c-Akt, Anti-phospho-Protein kinase B alpha |
Supplier: | United States Biological |
Supplier-Nr: | A1125-11B-PE |
Properties
Application: | FLISA, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | Phycoerythrin |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser129 of human AKT1 (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04456 | Matching products |
UniProt ID : | P31749 | Matching products |
Gene ID | GeneID 207 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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