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The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. Protein function: Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E- cadherin. [The UniProt Consortium]
Keywords:
Anti-ZEB2, Anti-SMADIP1, Anti-KIAA0569, Anti-HRIHFB2411, Anti-Smad-interacting protein 1, Anti-Zinc finger homeobox protein 1b, Anti-Zinc finger E-box-binding homeobox 2, ZEB2 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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