Anti-WTAP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-436A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A301-436A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein... more

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Product information "Anti-WTAP"

Protein function: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724). [The UniProt Consortium]

Keywords:	Anti-WTAP, Anti-hFL(2)D, Anti-KIAA0105, Anti-WT1-associated protein, Anti-Female-lethal(2)D homolog, Anti-Pre-mRNA-splicing regulator WTAP, Anti-Wilms tumor 1-associating protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-436A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: X. laevis, X. tropicalis)
Immunogen:	synthetic peptide. The epitope recognized by A301-436A-T maps to a region between residue 346 and 396 of human Wilms tumor 1 associated protein using the numbering given in entry NP_004897.2 (GeneID 9589).
Format:	Antigen Affinity Purified