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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F44169-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F44169-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the nuclear hormone receptor for... more
Product information "Anti-VDR"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. Protein function: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. [The UniProt Consortium]
Keywords: | Anti-VDR, Anti-NR1I1, Anti-Vitamin D3 receptor, Anti-1,25-dihydroxyvitamin D3 receptor, Anti-Nuclear receptor subfamily 1 group I member 1, VDR Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F44169 |
Properties
Application: | FC, WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 274-299 from the human protein was used as the immunogen for this VDR antibody. |
Format: | Purified |
Database Information
KEGG ID : | K08539 | Matching products |
UniProt ID : | P11473 | Matching products |
Gene ID : | GeneID 7421 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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