Anti-Vascular Endothelial Growth Factor-A (VEGF-A) (equine)

The Equine VEGF-A polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Equine VEGF-A ELISA. The Equine VEGF-A polyclonal antibody was produced in goats and is antigen-affinity purified. The reactivity by species is: (Bovine VEGF-A - Weak) (Canine VEGF-A - Weak) (Equine VEGF-A - Strong) (Mouse VEGF-A - Weak) (Rat VEGF-A - Weak) (Swine VEGF-A - Moderate). For research use only. Made in the USA Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor. [The UniProt Consortium]