Anti-USP2

Anti-USP2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-PACO46314.50 50 µg -

9 - 20 business days*

363.00€
 
USP2 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for... more
Product information "Anti-USP2"
USP2 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IF applications. USP2 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1 (PubMed:17290220, PubMed:19917254, PubMed:19838211). Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity (PubMed:17290220, PubMed:19838211). Has no deubiquitinase activity against p53/TP53 (PubMed:17290220). Prevents MDM2-mediated degradation of MDM4 (PubMed:17290220). Plays a role in the G1/S cell-cycle progression in normal and cancer cells (PubMed:19917254). Regulates the circadian clock by modulating its intrinsic circadian rhythm and its capacity to respond to external cues. Associates with clock proteins and deubiquitinates core clock component PER1 but does not affect its overall stability. Regulates the nucleocytoplasmic shuttling and nuclear retention of PER1 and its repressive role on the clock transcription factors CLOCK and ARNTL/BMAL1. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells. [The UniProt Consortium]
Keywords: Anti-USP2, Anti-UBP41, EC=3.4.19.12, Anti-Ubiquitin thioesterase 2, Anti-Deubiquitinating enzyme 2, Anti-41 kDa ubiquitin-specific protease, Anti-Ubiquitin carboxyl-terminal hydrolase 2, Anti-Ubiquitin-specific-processing protease 2
Supplier: Assay Genie
Supplier-Nr: PACO46314

Properties

Application: ELISA, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 2 protein (9-265AA)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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