Anti-USP16

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA021140.25	25 µl		-		7 - 10 business days*		320.00€
ATA-HPA021140.100	100 µl		-		7 - 10 business days*		450.00€

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Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific... more

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Product information "Anti-USP16"

Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 84%

Keywords:	Anti-MSTP039, Anti-Ubiquitin thioesterase 16, Anti-Deubiquitinating enzyme 16, Anti-Ubiquitin-processing protease UBP-M, Anti-Ubiquitin carboxyl-terminal hydrolase 16, Anti-Ubiquitin-specific-processing protease 16
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA021140

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: CLVLSLDNWS VWCYVCDNEV QYCSSNQLGQ VVDYVRKQAS ITTPKPAEKD NGNIELENKK LEKESKNEQE REKKENMAKE NPPMNSPCQI TVKGLSNLGN TCFFNAVMQN LSQTPVLREL LKEVKM (ATA-APrEST73927)