Anti-USP11

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-613A-T	10 µl (2 µg)		-		2 - 8 business days*		178.00€
A301-613A	100 µl		-		2 - 8 business days*		630.00€

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Protein function: Protease that can remove conjugated ubiquitin from target proteins and... more

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Product information "Anti-USP11"

Protein function: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome (PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'- linked ubiquitin chains (in vitro) (PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, PubMed:20233726). [The UniProt Consortium]

Keywords:	Anti-UHX1, Anti-USP11, Anti-Ubiquitin thioesterase 11, Anti-Deubiquitinating enzyme 11, Anti-Ubiquitin carboxyl-terminal hydrolase 11, Anti-Ubiquitin-specific-processing protease 11
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-613A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: pig, orangutan, rhesus monkey, white-tufted-ear marmoset, crab-eating macaque, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-613A-T maps to a region between residue 870 and 920 of human ubiquitin specific peptidase 11 using the numbering given in entry EAW59289.1 (GeneID 8237).
Format:	Antigen Affinity Purified