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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F40817-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F40817-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. UBE2I (Ubc9) is a member of the E2 family and is... more
Product information "Anti-UBC9"
In 1X PBS, pH 7.4, with 0.09% sodium azide. UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and chromosome segregation. Protein function: Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly- SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. [The UniProt Consortium]
Keywords: | Anti-p18, Anti-UBC9, Anti-UBE2I, EC=6.3.2.-, Anti-SUMO-protein ligase, Anti-Ubiquitin-protein ligase I, Anti-Ubiquitin carrier protein 9, Anti-Ubiquitin carrier protein I, Anti-SUMO-conjugating enzyme UBC9, Anti-Ubiquitin-conjugating enzyme E2 I, UBC9 Ant |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F40817 |
Properties
Application: | WB, IHC, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 1-30 from the human protein was used as the immunogen for this UBC9 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K10577 | Matching products |
UniProt ID : | P63279 | Matching products |
Gene ID : | GeneID 7329 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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