Anti-Tyrosine Kinase Receptor C (TrkC)(NT-3 growth factor receptor, Neurotrophic tyrosine kinase rec

TrkC is a member of the neurotrophic tyrosine receptor kinase family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3). Â Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Applicatons: Suitable for use in Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: 1:1000 -1:3000, Optimal dilutions to be determined by the researcher. Storage and Stability: , Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.