Anti-TXNRD1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-66881.60 60 µl -

7 - 16 business days*

198.00€
E-AB-66881.120 120 µl -

7 - 16 business days*

317.00€
E-AB-66881.200 200 µl -

7 - 16 business days*

525.00€
 
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein... more
Product information "Anti-TXNRD1"
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. Protein function: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid. [The UniProt Consortium]
Keywords: Anti-TR, Anti-TXNRD1, Anti-GRIM12, Anti-GRIM-12, EC=1.8.1.9, Anti-Thioredoxin reductase TR1, Anti-KM-102-derived reductase-like factor, Anti-Thioredoxin reductase 1, cytoplasmic, Anti-Gene associated with retinoic and IFN-induced mortality 12 protein, TXN
Supplier: Elabscience
Supplier-Nr: E-AB-66881

Properties

Application: IHC, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human TXNRD1

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-TXNRD1"
Write a review
or to review a product.
-30 %
Discount Promotion
Anti-Thioredoxin Reductase 1 Anti-Thioredoxin Reductase 1
624.00€ * 436.80€ *
Viewed