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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V8145SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. It reacts with a 75kDa melanocyte-specific gene... more
Product information "Anti-TRP1 / Tyrosinase-Related Protein-1, clone TYRP1/3280"
1 mg/ml in 1X PBS, BSA free, sodium azide free. It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Protein function: Plays a role in melanin biosynthesis (PubMed:22556244, PubMed:16704458). Catalyzes the oxidation of 5,6-dihydroxyindole-2- carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+) (PubMed:28661582). May regulate or influence the type of melanin synthesized (PubMed:22556244, PubMed:16704458). Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. [The UniProt Consortium]
Keywords: | Anti-TRP, Anti-TRP1, Anti-TRP-1, Anti-TYRP1, Anti-Catalase B, Anti-DHICA oxidase, Anti-Glycoprotein 75, Anti-Melanoma antigen gp75, Anti-Tyrosinase-related protein 1, Anti-5,6-dihydroxyindole-2-carboxylic acid oxidase, TRP1 / Tyrosinase-Related Protein-1 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V8145SAF |
Properties
Application: | ELISA, IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | TYRP1/3280 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A recombinant human partial protein (amino acids 257-377) |
Format: | Purified |
Database Information
KEGG ID : | K00506 | Matching products |
UniProt ID : | P17643 | Matching products |
Gene ID : | GeneID 7306 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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