Anti-TRIO

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA008157.25	25 µl		-		7 - 10 business days*		239.00€
ATA-HPA008157.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases... more

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Product information "Anti-TRIO"

Protein function: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:22155786, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202, PubMed:22155786). Plays a key role in the regulation of neurite outgrowth and lamellipodia formation (PubMed:32109419). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses. May act as a regulator of adipogenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 96%

Keywords:	Anti-TRIO, EC=2.7.11.1, Anti-PTPRF-interacting protein, Anti-Triple functional domain protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA008157

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MLVTHDYTAV KEDEINVYQG EVVQILASNQ QNMFLVFRAA TDQCPAAEGW IPGFVLGHTS AVIVENPDGT LKKSTSWHTA LRLRKKSEKK DKDGKREGKL ENGYRKSREG LSNKVSVKLL NPN (ATA-APrEST71476)