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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-FP4 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-TRIM30 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-TRIM30"
Anti-TRIM30 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TRIM30 from other sources has not been determined. Protein function: E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)- like complex is shown to mediate ubiquitination of CDKN1B ('Thr- 187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin- mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2. [The UniProt Consortium]
Keywords: | Anti-SS-A, Anti-RNF81, Anti-TRIM21, Anti-Ro(SS-A), EC=6.3.2.-, Anti-52 kDa Ro protein, Anti-RING finger protein 81, Anti-Sjoegren syndrome type A antigen, Anti-E3 ubiquitin-protein ligase TRIM21, Anti-Tripartite motif-containing protein 21, Anti-52 kDa ri |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-FP4 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse, rat |
Immunogen: | 24 amino acid synthetic peptide near the N-terminus of the mouse TRIM30. |
Format: | Purified |
Database Information
KEGG ID : | K10651 | Matching products |
UniProt ID : | P19474 | Matching products |
Gene ID : | GeneID 6737 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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-30 %
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-30 %
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