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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA005909.25 | 25 µl | - |
7 - 10 business days* |
300.00€
|
|||
ATA-HPA005909.100 | 100 µl | - |
7 - 10 business days* |
421.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase (PubMed:16352599).... more
Product information "Anti-TRIM25"
Protein function: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase (PubMed:16352599). Involved in innate immune defense against viruses by mediating ubiquitination of DDX58 and IFIH1 (PubMed:17392790, PubMed:30193849). Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region and may play a role in signal transduction that leads to the production of interferons in response to viral infection (PubMed:17392790, PubMed:23950712). Mediates 'Lys-63'- linked polyubiquitination of IFIH1 (PubMed:30193849). Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway (PubMed:16352599, PubMed:17069755). Mediates estrogen action in various target organs (PubMed:22452784). Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784). Plays a role in promoting the restart of stalled replication forks via interaction with the KHDC3L-OOEP scaffold and subsequent ubiquitination of BLM, resulting in the recruitment and retainment of BLM at DNA replication forks. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 72% and to rat: 71%
Keywords: | Anti-TRIM25, Anti-RING finger protein 147, Anti-Zinc finger protein 147, Anti-E3 ubiquitin/ISG15 ligase TRIM25, Anti-Estrogen-responsive finger protein, Anti-RING-type E3 ubiquitin transferase, Anti-Tripartite motif-containing protein 25 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA005909 |
Properties
Application: | ICC, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: FCPEHSECIC HICLVEHKTC SPASLSQASA DLEATLRHKL TVMYSQINGA SRALDDVRNR QQDVRMTANR KVEQLQQEYT EMKALLDASE TTSTRKIKEE EKRVNSKFDT IYQILLKKKS EIQTL (ATA-APrEST70901) |
Database Information
KEGG ID : | K10652 | Matching products |
UniProt ID : | Q14258 | Matching products |
Gene ID : | GeneID 7706 | Matching products |
Protein Atlas Nr. : | ENSG00000121060 |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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