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![Anti-TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB) (Azide free) (PE)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
T7948-10-PE.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to... more
Product information "Anti-TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB) (Azide free) (PE)"
TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90kD ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-TOB, Anti-TOB1, Anti-Protein Tob1, Anti-Transducer of erbB-2 1 |
Supplier: | United States Biological |
Supplier-Nr: | T7948-10-PE |
Properties
Application: | FLISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | Phycoerythrin |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptide selected from the N-terminal region of human TOB1 (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K14443 | Matching products |
UniProt ID : | P50616 | Matching products |
Gene ID | GeneID 10140 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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