Anti-TNFRSF11B

Anti-TNFRSF11B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA058613.100 100 µl

7 - 10 business days*

382.00€
 
Polyclonal Antibody against Human TNFRSF11B, Gene description: TNF receptor superfamily member... more
Product information "Anti-TNFRSF11B"
Polyclonal Antibody against Human TNFRSF11B, Gene description: TNF receptor superfamily member 11b, Alternative Gene Names: OCIF, OPG, TR1, Validated applications: ICC, Uniprot ID: O00300, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. [The UniProt Consortium] Mouse gene identity: 81% Rat gene identity: 81%
Keywords: Anti-OCIF, Anti-TNFRSF11B, Anti-Osteoprotegerin, Anti-Osteoclastogenesis inhibitory factor, Anti-Tumor necrosis factor receptor superfamily member 11B
Supplier: Atlas Antibodies
Supplier-Nr: HPA058613

Properties

Application: ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (ATA-APrEST95729)
Format: Affinity Purified

Handling & Safety

Storage: -20°C (+4 °C for short term storage)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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