Anti-TNFRSF11B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-834.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-KC-834.100	100 µl		-	-	Request delivery time estimate		295.00€

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Protein function: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function... more

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Product information "Anti-TNFRSF11B"

Protein function: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. [The UniProt Consortium]

Keywords:	Anti-Tumor necrosis factor receptor superfamily member 11B, Anti-Osteoclastogenesis inhibitory factor, Anti-Osteoprotegerin, TNFRSF11B Antibody
Supplier:	Absea
Supplier-Nr:	KC-834

Properties

Application:	IHC
Antibody Type:	Monoclonal
Clone:	3F12
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human TNFRSF11B
Format:	Solution

Database Information

KEGG ID :	K05148 \| Matching products
UniProt ID :	O00300 \| Matching products
Gene ID :	GeneID 4982 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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