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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| KP2128Y-100 | 100 µg | - | - |
3 - 8 business days* |
521.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted... more
Product information "Anti-TNF-a (cynomolgus)"
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6. [The UniProt Consortium]
| Keywords: | Anti-TNF, Anti-TNFA |
| Supplier: | Kingfisher Biotech |
| Supplier-Nr: | KP2128Y |
Properties
| Application: | WB, ELISA |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | monkey |
| Immunogen: | Recombinant Cynomolgus TNF-a |
| Format: | Antigen Affinity Purified |
Database Information
| UniProt ID : | P79337 | Matching products |
| Gene ID : | GeneID 102139631 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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