Anti-TLR3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-H26	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-TLR-3 Antibody was affinity purified. A BLAST analysis was used to suggest cross-reactivity... more

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Product information "Anti-TLR3"

Anti-TLR-3 Antibody was affinity purified. A BLAST analysis was used to suggest cross-reactivity with TLR3 with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with TRL3 from other sources has not been determined. This polyclonal antibody will not react with TRL1. Protein function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. [The UniProt Consortium]

Keywords:	Anti-TLR3, Anti-CD283, Anti-Toll-like receptor 3
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-H26

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	peptide corresponding to amino acids near the c-terminus of human TLR3.
Format:	Purified