Anti-TIMP4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R30263	100 µg		-	-	3 - 10 business days*		772.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. The tissue inhibitors of... more

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Product information "Anti-TIMP4"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. The tissue inhibitors of metalloproteinases(TIMPs) inhibit matrix metalloproteinases(MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. Expressed TIMP4 inhibits MMPs in vitro. TIMP4 gene is mapped to chromosome 3p25. TIMP-4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2. Protein function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9. [The UniProt Consortium]

Keywords:	Anti-TIMP4, Anti-TIMP-4, Anti-Metalloproteinase inhibitor 4, Anti-Tissue inhibitor of metalloproteinases 4, TIMP4 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R30263

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	An amino acid sequence from the C-terminus of human TIMP4 (RGHLPLRKEFVDIVQP) was used as the immunogen for this TIMP4 antibody.
Format:	Purified