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Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A300-816A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A300-816A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcriptional coactivator that interacts with numerous nuclear receptors and... more
Product information "Anti-TIF1 Alpha/TRIM24"
Protein function: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes. [The UniProt Consortium]
Keywords: | Anti-RNF82, Anti-TRIM24, Anti-TIF1-alpha, EC=2.3.2.27, Anti-RING finger protein 82, Anti-E3 ubiquitin-protein ligase TRIM24, Anti-Tripartite motif-containing protein 24, Anti-Transcription intermediary factor 1-alpha |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A300-816A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: bovine, horse, guinea pig, swine, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, african elephant, naked mole rat, small-eared galago, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A300-816A-T maps to a region between residue 1,000 and the C-terminus (residue 1050) of human Transcriptional Intermediary Factor 1 Alpha using the numbering given in entry NP_056989.2 (GeneID 8805). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K08881 | Matching products |
UniProt ID : | O15164 | Matching products |
Gene ID : | GeneID 8805 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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