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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3407-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V3407-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. It recognizes a... more
Product information "Anti-Thrombomodulin / CD141, clone THBD/1591"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas. Protein function: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [The UniProt Consortium]
Keywords: | Anti-TM, Anti-THRM, Anti-THBD, Anti-CD141, Anti-Fetomodulin, Anti-Thrombomodulin, Thrombomodulin Antibody / CD141 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3407 |
Properties
Application: | IHC (paraffin), FC, IF, ELISA, WB |
Antibody Type: | Monoclonal |
Clone: | THBD/1591 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody. |
Format: | Purified |
Database Information
KEGG ID : | K03907 | Matching products |
UniProt ID : | P07204 | Matching products |
Gene ID : | GeneID 7056 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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