Anti-SUMO2/3, clone S23MT-1

Anti-SUMO2/3, clone S23MT-1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7091IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Protein... more
Product information "Anti-SUMO2/3, clone S23MT-1"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Protein function: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744). [The UniProt Consortium]
Keywords: Anti-Smt3B, Anti-HSMT3, Anti-SUMO-2, Anti-SUMO-3, Anti-Sentrin-2, Anti-SMT3 homolog 2, Anti-Ubiquitin-like protein SMT3B, Anti-Small ubiquitin-related modifier 2
Supplier: NSJ Bioreagents
Supplier-Nr: V7091IHC

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: S23MT-1
Conjugate: No
Host: Mouse
Species reactivity: human, species reactivity (Expected: broad)
Immunogen: Recombinant human SUMO2 protein was used as the immunogen for this SUMO2/3 antibody. This antibody reacts with both SUMO2 and SUMO3.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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