Anti-SUMO-2 / SUMO-3, clone 10F1

Anti-SUMO-2 / SUMO-3, clone 10F1
Anti-SUMO-2 / SUMO-3, clone 10F1
Anti-SUMO-2 / SUMO-3, clone 10F1
Anti-SUMO-2 / SUMO-3, clone 10F1
Anti-SUMO-2 / SUMO-3, clone 10F1
Anti-SUMO-2 / SUMO-3, clone 10F1
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Save 30% on all primary antibodies by Arigo Biolaboratories!

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*1 Offer expires 16/12/2024
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
ARG57103.50 50 µl - -

6 - 14 business days*

30 %
488.00€
341.60€
 
Protein function: Ubiquitin-like protein that can be covalently attached to proteins as a monomer... more
Product information "Anti-SUMO-2 / SUMO-3, clone 10F1"
Protein function: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451 (PubMed:26524494). This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744). [The UniProt Consortium]
Keywords: Anti-Smt3B, Anti-HSMT3, Anti-SUMO-2, Anti-SUMO-3, Anti-Sentrin-2, Anti-SMT3 homolog 2, Anti-Ubiquitin-like protein SMT3B, Anti-Small ubiquitin-related modifier 2
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG57103

Properties

Application: WB, ICC, IF, IHC (paraffin), FC
Antibody Type: Monoclonal
Clone: 10F1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant fragment around aa. 1-93 of Human SUMO-2 / SUMO-3
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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