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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
030662.100 | 100 µl | - | - |
3 - 19 business days* |
682.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
STAT3: signal transducer and activator of transcription 3 (acute-phase response factor). The... more
Product information "Anti-STAT3 (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF, F"
STAT3: signal transducer and activator of transcription 3 (acute-phase response factor). The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-APRF, Anti-STAT3, Anti-Acute-phase response factor, Anti-Signal transducer and activator of transcription 3 |
Supplier: | United States Biological |
Supplier-Nr: | 030662 |
Properties
Application: | ELISA, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 13B740 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Purified recombinant fragment of STAT3 expressed in E. coli. |
Database Information
KEGG ID : | K04692 | Matching products |
UniProt ID : | P40763 | Matching products |
Gene ID : | GeneID 6774 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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