Anti-SSTR2(tidutamab biosimilar) mAb

Item number Size Datasheet Manual SDS Delivery time Quantity Price
DIM-BME100127.50 50 µg - -

7 - 16 business days*

115.00€
DIM-BME100127.100 100 µg - -

7 - 16 business days*

227.00€
 
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis... more
Product information "Anti-SSTR2(tidutamab biosimilar) mAb"
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization. [The UniProt Consortium]
Keywords: Anti-SS-2-R, Anti-SS2-R, Anti-SS2R, Anti-SST2, Anti-SRIF-1, Anti-SSTR2(tidutamab biosimilar) mAb
Supplier: DIMA
Supplier-Nr: BME100127

Properties

Antibody Type: Monoclonal
Conjugate: No
Host: Chimeric Humanized
Species reactivity: human
Format: Lyophilized

Database Information

CAS : 12| Matching products
UniProt ID : P30874 | Matching products

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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