Anti-SSTR2 antibody(DMC428), IgG1 Chimeric mAb

Anti-SSTR2 antibody(DMC428), IgG1 Chimeric mAb
Item number Size Datasheet Manual SDS Delivery time Quantity Price
DIM-DMC100428.10 10 µg - -

7 - 16 business days*

139.00€
DIM-DMC100428.100 100 µg - -

7 - 16 business days*

624.00€
DIM-DMC100428.500 500 µg - -

7 - 16 business days*

1,876.00€
 
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis... more
Product information "Anti-SSTR2 antibody(DMC428), IgG1 Chimeric mAb"
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization. [The UniProt Consortium]
Keywords: Anti-SRIF-1, Anti-SS2R, Anti-SSTR2 antibody(DMC428), IgG1 Chimeric mAb
Supplier: DIMA
Supplier-Nr: DMC100428

Properties

Antibody Type: Monoclonal
Clone: DMC428
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Lyophilized

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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