Anti-SSTR1 Somatostatin Receptor 1

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Somatostatin receptor type 1 is a protein that in humans is encoded by the SSTR1 gene. The SSTR1 gene is mapped to chromosome 14. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach. Protein function: Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. [The UniProt Consortium]