Anti-SREBP1, clone 2A4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG62627.50	50 µl		-	-	6 - 14 business days*		399.00€
ARG62627.100	100 µl		-	-	6 - 14 business days*		575.00€

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Protein function: [Sterol regulatory element-binding protein 1]: Precursor of the transcription... more

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Product information "Anti-SREBP1, clone 2A4"

Protein function: [Sterol regulatory element-binding protein 1]: Precursor of the transcription factor form (Processed sterol regulatory element- binding protein 1), which is embedded in the endoplasmic reticulum membrane (PubMed:32322062). Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis. {ECO:0000250, UniProtKB:Q9WTN3, ECO:0000269, PubMed:32322062}. [The UniProt Consortium]

Keywords:	Anti-BHLHD1, Anti-bHLHd1, Anti-SREBP-1 {ECO:0000303\|PubMed:8402897}, Anti-Class D basic helix-loop-helix protein 1, Anti-Transcription factor SREBF1 {ECO:0000305}, Anti-Processed sterol regulatory element-binding protein 1 {ECO:0000305}, Anti-Sterol regul
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG62627

Properties

Application:	FC, ICC, IF, WB
Antibody Type:	Monoclonal
Clone:	2A4
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse, rat, bovine, guinea pig, rabbit
Immunogen:	6 His-tag fusion protein of human SREBP1 corresponding to amino acids 301-407
MW:	122 kD
Format:	Purified