Anti-SPTLC1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA063907.25 25 µl -

7 - 10 business days*

239.00€
ATA-HPA063907.100 100 µl -

7 - 10 business days*

477.00€
 
Protein function: Serine palmitoyltransferase (SPT) (PubMed:19416851). The heterodimer formed... more
Product information "Anti-SPTLC1"
Protein function: Serine palmitoyltransferase (SPT) (PubMed:19416851). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core (PubMed:19416851). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference (PubMed:19416851). The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA (PubMed:19416851). The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (PubMed:19416851). Required for adipocyte cell viability and metabolic homeostasis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 88% and to rat: 86%
Keywords: Anti-SPT1, Anti-LCB1, Anti-SPT 1, Anti-LCB 1, Anti-SPTLC1, Anti-Serine palmitoyltransferase 1, Anti-Serine-palmitoyl-CoA transferase 1, Anti-Long chain base biosynthesis protein 1
Supplier: Atlas Antibodies
Supplier-Nr: HPA063907

Properties

Application: WB, ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GISGLKVVGE SLSPAFHLQL EESTGSREQD VRLLQEIVDQ CMNRSIALTQ ARYLEKEEKC LPPPSIRVVV TVE (ATA-APrEST90057)

Database Information

KEGG ID : K00654 | Matching products
UniProt ID : O15269 | Matching products
Gene ID : GeneID 10558 | Matching products
Protein Atlas Nr. : ENSG00000090054

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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