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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S5360-18A.100 | 100 µg | - | - |
3 - 19 business days* |
606.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SOS1 (son of sevenless homolog 1) is a ubiquitously expressed 150kD intracellular protein and... more
Product information "Anti-Son of Sevenless 1 (SOS1, Son of Sevenless Homolog 1, SOS-1)"
SOS1 (son of sevenless homolog 1) is a ubiquitously expressed 150kD intracellular protein and bifunctional guanine nucleotide exchange factor (GEF), which plays a role in growth and differentiation signalling pathways and in actin reorganization, by acting as a regulator of Ras and Rac/Rho GTPases. Mutations in the SOS1 gene are responsible for the rare oral overgrowth condition known as gingival fibromatosis 1 (GINGF1), and also the cause of the relatively common autosomal dominant disorder Noonan syndrome type 4 (NS4), characterized by short stature, congenital heart malformation, bleeding diathesis and distinctive facial features. Applications: Suitable for use in ELISA, Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1ug/ml Detects a band of ~150kD in K562 and RAJI cell lysates under reducing conditions., Optimal dilutions to be determined by the researcher. Recommended secondary antibodies: I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo, I1904-06H: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo, I1904-14C: IgG, Fc (HRP) Pab Gt xMo, I1904-19C: IgG, F(ab')2 (HRP) Pab Gt xMo, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Son of sevenless homolog 1 |
Supplier: | United States Biological |
Supplier-Nr: | S5360-18A |
Properties
Application: | ELISA, IF, WB |
Antibody Type: | Monoclonal |
Clone: | 10F445 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptide corresponding to aaTHPSMHRDGPPLLENAHSS of human SOS1. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K03099 | Matching products |
UniProt ID : | Q07889 | Matching products |
Gene ID : | GeneID 6654 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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