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![Anti-Sodium channel Nav1.7](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
N0530-26A.100 | 100 µg | - | - |
3 - 19 business days* |
863.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Voltage-gated sodium channel subunit alpha Nav1.7 (Nav1.7) is a multi-pass membrane protein... more
Product information "Anti-Sodium channel Nav1.7"
Voltage-gated sodium channel subunit alpha Nav1.7 (Nav1.7) is a multi-pass membrane protein containing a single IQ domain that belongs to the sodium channel family. NAV1.7 localizes to the terminal ends of sensory neurons and is believed to have a role in inflammatory pain development and mechanisms. It serves to regulate excitable membrane voltage-dependent Na+ ion permeability. There is a strong probability that Nav1.7 is involved in the transmission of nociceptive information, a suggested involvement supported by its role in a variety of chronic pain neuropathies induced by damage to the peripheral nerves. Nav1.7 is predominantly observed in dorsal root ganglion, and sensory and sympathetic neurons. Lower levels of the protein have been observed in MTC cell line, C-cell carcinoma, and smooth muscle cells. Defects in Nav1.7 expression are causal to several diseases such as autosomal recessive congenital indifference pain, primary erythermalgia, and paroxysmal extreme pain disorder or PEPD. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested. , Recommended Dilutions: Immunohistochemistry (Paraffin): 1:400 detects Sodium channel Nav1.7 in rat cerebellum tissue. Heat induced antigen retrieval with sodium citrate buffer, pH 6.0 is recommended., Optimal dilutions to be determined by the researcher. Positive Control: Rat cerebellum tissue, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-PN1, Anti-NENA, Anti-SCN9A, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium channel protein type 9 subunit alpha, Anti-Sodium channel protein type IX subunit alpha |
Supplier: | United States Biological |
Supplier-Nr: | N0530-26A |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 11C247 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, rat |
Immunogen: | Recombinant protein corresponding to human Nav1.7. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04841 | Matching products |
UniProt ID : | Q15858 | Matching products |
Gene ID | GeneID 6335 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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