Anti-SMAD2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-KC-3737.50 50 µl - -

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206.00€
ABS-KC-3737.100 100 µl - -

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295.00€
 
Protein function: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and... more
Product information "Anti-SMAD2"
Protein function: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
Keywords: Anti-Mothers against decapentaplegic homolog 2, Anti-MAD homolog 2, Anti-Mothers against DPP homolog 2, Anti-JV18-1, Anti-Mad-related protein 2, Anti-hMAD-2, Anti-SMAD family member 2, Anti-SMAD 2, Anti-Smad2, Anti-hSMAD2, SMAD2 Antibody
Supplier: Absea
Supplier-Nr: KC-3737

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: 3C7
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Human SMAD2 peptide
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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