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![Anti-Smac / Diablo, clone RM271 (recombinant antibody)](https://www.biomol.com/media/image/dc/0f/45/NSJ-R20288-0-1ML_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R20288-0.1ML | 100 µl | - | - |
3 - 10 business days* |
737.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Antibody in PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide. This recombinant Smac antibody... more
Product information "Anti-Smac / Diablo, clone RM271 (recombinant antibody)"
Antibody in PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide. This recombinant Smac antibody reacts to human Smac (Diablo homolog, mitochondrial). Protein function: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis- inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance. [The UniProt Consortium]
Keywords: | Anti-Smac, Anti-SMAC, Anti-DIABLO, Anti-Diablo homolog, mitochondrial, Anti-Direct IAP-binding protein with low pI, Anti-Second mitochondria-derived activator of caspase, Recombinant Smac Antibody / Diablo |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R20288 |
Properties
Application: | WB, IHC |
Antibody Type: | Monoclonal |
Clone: | RM271 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A peptide corresponding to the C-terminus of human Smac/Diablo was used as the immunogen for this recombinant Smac antibody. |
Format: | Purified |
Database Information
KEGG ID : | K10522 | Matching products |
UniProt ID : | Q9NR28 | Matching products |
Gene ID | GeneID 56616 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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