Anti-SIRT3

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG57750.100	100 µl		-	-	6 - 14 business days*		30 %	624.00€ 436.80€

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Protein function: NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852,... more

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Product information "Anti-SIRT3"

Protein function: NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090, PubMed:19535340). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090). Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5PO (PubMed:16788062, PubMed:18680753, PubMed:24121500, PubMed:24252090, PubMed:19535340). Contributes to the regulation of the cellular energy metabolism (PubMed:24252090). Important for regulating tissue-specific ATP levels (PubMed:18794531). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301). [The UniProt Consortium]

Keywords:	Anti-SIRT3, Anti-SIR2L3, Anti-hSIRT3, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3, Anti-NAD-dependent protein deacetylase sirtuin-3, mitochondrial
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57750

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide from Human SIRT3
MW:	28 kD
Format:	Affinity Purified