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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-25316 | 50 µg | - | - |
3 - 15 business days* |
706.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SirT1 (UniProtKB/Swiss Prot entry Q96EB6) is a NAD dependent deacetylase, which regulates... more
Product information "Anti-SIRT1"
SirT1 (UniProtKB/Swiss Prot entry Q96EB6) is a NAD dependent deacetylase, which regulates processes such as apoptosis and muscle differentiation by the deacetylation of key regulatory proteins. Deacetylation of lysine 382 of p53/TP53 by Sirt1 impairs its ability to induce the proapoptotic program and modulate cell senescence, whereas deacetylation of TAF1B represses rDNA transcription by the RNA polymerase I. SirT1 is also involved in HES1 and HEY2 mediated transcriptional repression and inhibits skeletal muscle differentiation by deacetylating PCAF and MYOD1. SirT1 is recruited to the nuclear bodies via its interaction with PML
Keywords: | hSIR2, SIR2alpha, SIR2L1, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 25316 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Conjugate: | No |
Species reactivity: | human |
Immunogen: | human SIRT1 (NAD dependent deacetylase sirtuin 1) using a synthetic peptide |
Format: | Purified |
Database Information
KEGG ID : | K11411 | Matching products |
UniProt ID : | Q96EB6 | Matching products |
Gene ID | GeneID 23411 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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