Anti-SHMT2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-351A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A305-351A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Contributes to the de novo mitochondrial thymidylate biosynthesis pathway via... more

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Product information "Anti-SHMT2"

Protein function: Contributes to the de novo mitochondrial thymidylate biosynthesis pathway via its role in glycine and tetrahydrofolate metabolism. Thymidylate biosynthesis is required to prevent uracil accumulation in mtDNA (PubMed:21876188). Interconversion of serine and glycine (PubMed:25619277). Associates with mitochondrial DNA (PubMed:18063578). Plays a role in the deubiquitination of target proteins as component of the BRISC complex (PubMed:24075985). Required for IFNAR1 deubiquitination by the BRISC complex (PubMed:24075985). [The UniProt Consortium]

Keywords:	Anti-SHMT, Anti-SHMT2, Anti-Serine methylase, Anti-Glycine hydroxymethyltransferase, Anti-Serine hydroxymethyltransferase, mitochondrial
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-351A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	synthetic peptide. The epitope recognized by A305-351A-T maps to a region between residue 454 to 504 of human Serine hydroxymethyltransferase, mitochondrial using the numbering given in entry P34897.3 (GeneID 6472).
Format:	Antigen Affinity Purified