Anti-SGPL1

Anti-SGPL1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB15745.20 20 µl -

9 - 20 business days*

149.00€
 
Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate,... more
Product information "Anti-SGPL1"
Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339). Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro- inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP. Seems to play a role in establishing neuronal contact sites and axonal maintenance. [The UniProt Consortium]
Keywords: Anti-hSPL, Anti-S1PL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate aldolase
Supplier: Assay Genie
Supplier-Nr: CAB15745

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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