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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES13132.50 | 50 µl | - | - |
10 - 14 business days* |
169.00€
|
||
| ELK-ES13132.100 | 100 µl | - | - |
10 - 14 business days* |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate,... more
Product information "Anti-SGPL1"
Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339). Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro- inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP. Seems to play a role in establishing neuronal contact sites and axonal maintenance. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Endoplasmic reticulum membrane , Single-pass type III membrane protein , Cytoplasmic side .
| Keywords: | Anti-S1PL, Anti-hSPL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate aldolase, SGPL1 rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES13132 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Synthesized peptide derived from human SGPL1 AA range: 393-443 |
| MW: | 60 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K01634 | Matching products |
| UniProt ID : | O95470 | Matching products |
| Gene ID : | GeneID 8879 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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